
Bone diseases
Illnesses that cause an underproduction of bone mass, such as osteoporosis, an overproduction of bone, such as PAGET’S DISEASE and ACROMEGALY, or abnormal bone, seen to varying extents in OSTEOPOROSIS, fibrous dysplasia, and Paget’s disease. Disorders of bone may be induced by nonendocrine causes, such as cancer, infection, vitamin deficiency, disorders of cartilage production, and genetic defects.
Bone density can be measured using a variety of techniques, most commonly with the dual-energy X-ray absorptiometry scan (DEXA SCAN). Bone biopsies are helpful in some cases. Blood and urine tests can help to determine the activities of the major cells within the bone, namely, the osteoclasts, which help to break down the bone, and the osteoblasts, which help to create the new bone.
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